王瑞瑶
高级副教授 西浦慧湖药学院 Ruiyao.Wang@xjtlu.edu.cn
王瑞瑶博士专注于基于晶体工程和配位化学的药物化学研究，致力于开发新型药物。其当前研究聚焦于开发新型药物共晶、抗肿瘤药物的药物-药物共晶、靶向抗肿瘤铂（IV）络合物前药及药物配方。此前曾在加拿大皇后大学任职。至今王博士已发表150余篇研究论文，并拥有一项美国和加拿大专利及一项中国专利。
发表文献
    Wong, Jonathan M.; Zhang, Ruizhong; Xie, Peidong; Yang, Liuqing; Zhang, Minlin; Zhou, Ruixue; Wang, Ruiyao; Shen, Yue; Yang, Bing; Wang, Hong-Bo; Ding, Zhifeng; Revealing Crystallization Induced Blue Shift Emission of a Di‐Boron Complex by Enhanced Photoluminescence and Electrochemiluminescence. Angew. Chem. Int. Ed.. Accepted Author Manuscript. doi:10.1002/anie.202007588.
    Hanifehpour, Younes; Mirtamizdoust, Babak; Ahmadi, Hossein; Wang, Ruiyao; Joo, Sang Woo; Sonochemical synthesis, crystal structure, and DFT calculation of an innovative nanosized Pb(II)-azido metal-organic coordination polymer as a precursor for preparation of PbO nanorod. Chemical Papers (2020), Ahead of Print.
    Hanifehpour, Younes; Mirtamizdoust, Babak; Ahmadi, Hossein; Wang, Ruiyao; Joo, Sang Woo; Ultrasonic-assisted synthesis, characterizing the structure and DFT calculation of a new Pb(II)-chloride metal-ligand coordination polymer as a precursor for preparation of α-PbO nanoparticles. Journal of Molecular Structure (2021), 1224, 129031.
    Chao, Meng-Yao; Chen, Jing; Wu, Xiao-Yu; Wang, Rui-Yao; Wang, Pei-Pei; Ding, Lifeng; Young, David J.; Zhang, Wen-Hua; Unconventional Pyridyl Ligand Inclusion within a Flexible Metal-Organic Framework Bearing an N,N'-Diethylformamide (DEF)-Solvated Cd5 Cluster Secondary Building Unit. ChemPlusChem (2020), 85(3), 503-509.
    Yang, Siyuan; Chen, Linjiang; Holden, Daniel; Wang, Ruiyao; Cheng, Yuanyuan; Wells, Mona; Cooper, Andrew I.; Ding, Lifeng, Understanding the effect of host flexibility on the adsorption of CH4, CO2 and SF6 in porous organic cages. Zeitschrift fuer Kristallographie - Crystalline Materials (2019), 234(7-8), 547-555.
    Wang, Ruiyao; Aquino, Manuel A. S. 1,3-Bis(2,4,6-trimethylphenyl)imidazolium perchlorate. IUCrData (2019), 4(4), x190494.
    Abdou, Moaz M.; Matziari, Magdalini; O'Neill, Paul M.; Amigues, Eric; Zhou, Ruixue; Wang, Ruiyao; Ali, Basem F. Methyl 3-(4-hydroxyphenyl)propionate. IUCrData (2018), 3(11), x181662.
    Ge, Yuxin; Zhou, Hao; Ji, Yujin; Ding, Lifeng; Cheng, Yuanyuan; Wang, Ruiyao; Yang, Siyuan; Liu, Yufeng; Wu, Xiaoyu; Li, Youyong. Understanding Water Adsorption and the Impact on CO2 Capture in Chemically Stable Covalent Organic Frameworks. Journal of Physical Chemistry C (2018), 122(48), 27495-27506.
    Zhang, Ruizhong; Tong, Feng; Yang, Liuqing; Adsetts, Jonathan Ralph; Yan, Tianhao; Wang, Ruiyao; Ding, Zhifeng; Wang, Hong-Bo. Facile synthesis and efficient electrochemiluminescence of a readily accessible pyridopyrimidine. Chemical Communications (2018), 54(71), 9897-9900.
    Aquino, Manuel A. S.; Minaker, Samuel A.; Wang, Ruiyao. 1,3-Bis(2,6-diisopropylphenyl) imidazolium perchlorate. IUCrData (2018), 3, x180516.
    Hanifehpour, Younes; Mirtamizdoust, Babak; Wang, Ruiyao; Anbarteh, Saeed; Joo, Sang Woo, A Nano Nickel(II) Metal-Organic Coordination Compound for Nano Nickel (II) Oxide: Sonochemical Synthesis and Characterization. Journal of Inorganic and Organometallic Polymers and Materials (2017), 27(4), 1045-1052.
    Essoun, Ernest; Wang, Ruiyao; Aquino, Manuel A. S. Disassembly of diruthenium(II,III) tetraacetate with P-N donor ligands. Inorganica Chimica Acta (2017), 454, 97-106.
    Kandel, Ramjee; Huynh, Keith; Dalgliesh, Lauren; Wang, Ruiyao; Jessop, Philip G. Contrasting connectivity of amidine and phosphaamidine (1,3-P,N) Cu(I) complexes. Inorganica Chimica Acta (2016), 445, 117-123.
    Chen, Xiaocui; Han, Shumin; Wang, Ruiyao; Li, Yuan. Four supramolecular isomers of dichloridobis(1,10-phenanthroline)cobalt(II): synthesis, structure characterization and isomerization. Acta Crystallographica, Section C: Structural Chemistry (2016), 72(1), 6-13.
    Chen, Xiaocui; Wang, Yue; Han, Shumin; Wei, Yongju; Wang, Ruiyao, 4,4'-Bipyridine-1,1'-diium acetylenedicarboxylate: a new member of the (H2bipy)[Cu(ox)2] (bipy is 4,4'-bipyridine and ox is oxalate) family. Acta Crystallographica, Section C: Structural Chemistry (2015), 71(5), 357-362.
    Ang, M. Trisha C.; Phan, Lam; Alshamrani, Aliyah K.; Harjani, Jitendra R.; Wang, Ruiyao; Schatte, Gabriele; Mosey, Nicholas J.; Jessop, Philip G. Contrasting Reactivity of CS2 with Cyclic vs. Acyclic Amidines. European Journal of Organic Chemistry (2015), 2015(33), 7334-7343.
    Kong, Xianqi; Tang, Aaron; Wang, Ruiyao; Ye, Eric; Terskikh, Victor; Wu, Gang. Are the amide bonds in N-acyl imidazoles twisted? A combined solid-state 17O NMR, crystallographic, and computational study. Canadian Journal of Chemistry (2015), 93(4), 451-458.
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研究领域
单晶培养及分子结构测定
新型晶型药物开发
抗肿瘤药物的新型药物共晶体开发
基于铂(IV)配合物的靶向抗肿瘤前药开发
新药晶型筛选及作用靶点研究
应用场景
药物与材料的晶体结构与分子结构分析，药物晶型，分子手性
工作经历
2012年至今 西交利物浦大学化学系副教授
2002至2012年 加拿大皇后大学化学系X射线实验室经理/部门晶体学家
2000年至2002年 加拿大皇后大学化学系助理研究员
1998至2000年 美国亚利桑那大学化学系博士后
1983至1998年 中国河北农业大学艺术与科学学院化学系助教/讲师/副系主任
教育背景
1997年 博士，北京大学 1990年 硕士，中国科学院长春应用化学研究所
科研项目
to be updated
产学研合作
to be updated
专利项目
ZL201910103268.0 制备高性能金属卤化物钙钛矿薄膜的溶剂、方法及应用

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